A nicotinic channel blocker.

AstraZeneca, Targacept commence enrollment in TC-5214 Stage 3 clinical advancement for MDD Targacept and AstraZeneca, Inc malegra fxt ., today announced the enrollment of the first individual in the Phase 3 clinical development plan for TC-5214, a nicotinic channel blocker. The Stage 3 program, known as the Renaissance Plan, is made to support the prepared second half of 2012 submitting of a fresh drug program with the U.S. Food and Medication Administration for TC-5214 as an adjunct treatment for main depressive disorder in individuals with an inadequate response to first-collection therapy with a selective serotonin reuptake inhibitor or serotonin/norephinephrine reuptake inhibitor .

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