Gradual dose titration at the start of treatment may minimize side effects such as flu-like symptoms that may occur with interferon beta therapy1. Flu-like symptoms occur in 40 percent of patients2 and are typically present within the first few days of the starting treatment increase female desire . Most patients also experience reactions at the injection site, predominantly mild inflammation. While both side effects in most cases are reversible and decrease over time, they have shown that reduce the potential for concordance. In a retrospective study in 281 patients at the injection site reactions and flu-like symptoms among the top three among the top three causes of interruption of interferon beta therapy3.
40 percent ofebif Initiation pack for patients with relapsing multiple sclerosisMerck Serono has announced the launch of a new package of Rebif in patients with relapsing-remitting multiple sclerosis . It is important if patients interferon beta therapy, the dose gradually increased over a period of four weeks, as this will help minimize potential side effects start. The new packaging consists of 12 syringes at the recommended dosage staged titration titration and reduce losses, as a patient starts therapy.
The study will the effect of multiple dose and regimen ITMN-191 in combination with pegylated interferon alpha-2a ) and ribavirin on safety, efficacy, pharmacokinetics and viral kinetics optionally dealt compared to effects in patients only with the pegylated interferon alpha-2a and ribavirin.