I am very encouraged our strategy of restoring a critical enzyme that’s depleted in advanced center failure may lead to fresh treatment options for those patients that continue to decline despite the best standard drug and device therapies, said Mariell Jessup, M.D., Professor of Medication at the University of Pennsylvania’s School of Medicine, who was the main investigator and lead writer of the study. Predicated on these results we are encouraged that MYDICAR may one day fill this need.12).A straightforward approach to diagnosis is required. Chronic daily headache can be a common condition. Establishing the current presence of chronic daily headache requires documentation of more than 15 days per month of prolonged headaches . Most cases of persistent daily headache are due to primary headache, but other causes such as for example structural lesions must be considered; most instances of primary headache that are troublesome are because of chronic migraine. Treatments for patients with chronic migraine can be found now.