There are methods currently pharmacologically manipulate molecules such as miR-21, said the Dr. Nancy B. And Jake L generic drugs . Hamon Center for Basic Research in Cancer and leads the Near Burg Family Center for Basic and Clinical Research in Pediatric Oncology. More research is needed before we know whether transferable to humans transmitted to humans, but it is possible that a drug designed to to inhibit miR-21 could help cancer at bay. .
In animals with cancer, the results showed that too much miR-21, or overexpression promotes the formation, growth and survival of new tumors by turning off certain genes that normally die off for cancer cells. In fact, at 18 weeks old, had the study group. With overexpressed miR-21 significantly more tumors than their lung – cancer-carrying littermates with normal levels of miR-21 Healthy rodents designed to overexpress miR-21 did not develop cancer. These results indicate that overexpression of miR-21 alone is not initiate initiate tumors in a healthy animal, but it appears that miR-21 the growth and survival increased existing lung cancer, said Dr. Hatley a Pediatric Scientist Development Program Fellow at the Eunice Kennedy Shriver National Institute of Child Health and Human Development sponsored. Eric Olson, chairman of molecular biology at UT Southwestern and the study’s senior author, said the experiments also show that deleting miR-21 sensitizes the cancer cells to animals in a specific type of chemotherapy, suggesting that inhibition of miR – 21 in lung cancer patients could be of therapeutic benefit.
Effective chelation on by serum ferritin level levels reduces maintaining of approximately 1,000 ng / mL.